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Catalytically Active Monomer of Glutathione S-Transferase π and Key Residues Involved in the Electrostatic Interaction between Subunits

Human glutathione transferase π (GST π) has been crystallized as a homodimer, with a subunit molecular mass of ∼23 kDa; however, in solution the average molecular mass depends on protein concentration, approaching that of monomer at <0.03 mg/ml, concentrations typically used to measure catalytic...

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Detalhes bibliográficos
Main Authors: Huang, Yu-chu, Misquitta, Stephanie, Blond, Sylvie Y., Adams, Elizabeth, Colman, Roberta F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583305/
https://ncbi.nlm.nih.gov/pubmed/18796433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805484200
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