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Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S-transferase π

Monobromobimane (mBBr), functions as a substrate of porcine glutathione S-transferase π (GST π): The enzyme catalyzes the reaction of mBBr with glutathione. S-(Hydroxyethyl)bimane, a nonreactive analog of monobromobimane, acts as a competitive inhibitor with respect to mBBr as substrate but does not...

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Detalhes bibliográficos
Main Authors: Ralat, Luis A., Colman, Roberta F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366952/
https://ncbi.nlm.nih.gov/pubmed/14573868
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