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Virulence plasmids of enteroinvasive Escherichia coli and Shigella flexneri integrate into a specific site on the host chromosome: integration greatly reduces expression of plasmid-carried virulence genes.

The ability of enteroinvasive Escherichia coli and Shigella flexneri to cause disease depends on the presence of a large virulence plasmid (pINV). In this report we show that pHN280, the pINV of the O135:K-:H- enteroivasive strain E. coli HN280, and pWR100, the pINV of S. flexneri serotype 5 strain...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Zagaglia, C, Casalino, M, Colonna, B, Conti, C, Calconi, A, Nicoletti, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1997431/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.3.792-799.1991
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