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Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri

Abstract Shigella, the aetiological agent of human bacillary dysentery, controls the expression of its virulence determinants through an environmentally stimulated cascade of transcriptional activators. VirF is the leading activator and is essential for proper virulence expression. In this work, we...

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Autors principals: Rita Trirocco, Martina Pasqua, Angela Tramonti, Bianca Colonna, Alessandro Paiardini, Gianni Prosseda
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2023-08-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-023-40023-w
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