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Supraphysiologic extracellular pressure inhibits intestinal epithelial wound healing independently of luminal nutrient flow
INTRODUCTION: Luminal pressure may injure the gut mucosa in obstruction, ileus, or IBD. METHODS: We formed Roux-en-Y anastomoses in 19 mice, creating proximal and defunctionalized partially obstructed limbs and a distal limb to vary luminal pressure and flow. We induced mucosal ulcers by serosal ace...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583260/ https://ncbi.nlm.nih.gov/pubmed/18954600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2008.07.016 |
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