Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation

The state of the transcriptome reflects a balance between mRNA production and degradation. Yet how these two regulatory arms interact in shaping the kinetics of the transcriptome in response to environmental changes is not known. We subjected yeast to two stresses, one that induces a fast and transi...

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Main Authors: Shalem, Ophir, Dahan, Orna, Levo, Michal, Martinez, Maria Rodriguez, Furman, Itay, Segal, Eran, Pilpel, Yitzhak
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583085/
https://ncbi.nlm.nih.gov/pubmed/18854817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.59
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