The LIM-Only Protein FHL2 Mediates Ras-Induced Transformation through Cyclin D1 and p53 Pathways

BACKGROUND: Four and a half LIM-only protein 2 (FHL2) has been implicated in multiple signaling pathways that regulate cell growth and tissue homeostasis. We reported previously that FHL2 regulates cyclin D1 expression and that immortalized FHL2-null mouse embryo fibroblasts (MEFs) display reduced l...

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Detalhes bibliográficos
Main Authors: Labalette, Charlotte, Nouët, Yann, Levillayer, Florence, Armengol, Carolina, Renard, Claire-Angélique, Soubigou, Guillaume, Xia, Tian, Buendia, Marie-Annick, Wei, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583050/
https://ncbi.nlm.nih.gov/pubmed/19018287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003761
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