Deficiency of the LIM-Only Protein FHL2 Reduces Intestinal Tumorigenesis in Apc Mutant Mice

BACKGROUND: The four and a half LIM-only protein 2 (FHL2) is capable of shuttling between focal adhesion and nucleus where it signals through direct interaction with a number of proteins including β-catenin. Although FHL2 activation has been found in various human cancers, evidence of its functional...

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Detalhes bibliográficos
Main Authors: Labalette, Charlotte, Nouët, Yann, Levillayer, Florence, Colnot, Sabine, Chen, Ju, Claude, Valere, Huerre, Michel, Perret, Christine, Buendia, Marie-Annick, Wei, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860980/
https://ncbi.nlm.nih.gov/pubmed/20442768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010371
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