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Molecular Evolution of the Tre Recombinase
Here we report the generation of Tre recombinase through directed, molecular evolution. Tre recombinase recognizes a pre-defined target sequence within the LTR sequences of the HIV-1 provirus, resulting in the excision and eradication of the provirus from infected human cells. We started with Cre, a...
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| Formato: | Artigo |
| Idioma: | Inglês |
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MyJove Corporation
2008
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583018/ https://ncbi.nlm.nih.gov/pubmed/19066582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/791 |
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