Altered Endocrine and Autocrine Metabolism of Vitamin D in a Mouse Model of Gastrointestinal Inflammation

The active form of vitamin D, 1,25-dihydroxyvitamin D(3), [1,25(OH)(2)D(3)] has potent actions on innate and adaptive immunity. Although endocrine synthesis of 1,25(OH)(2)D(3) takes place in the kidney, the enzyme that catalyzes this, 25-hydroxyvitamin D-1α-hydroxylase (CYP27b1 in humans, Cyp27b1 in...

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Autores principales: Liu, Nancy, Nguyen, Lisa, Chun, Rene F., Lagishetty, Venu, Ren, Songyang, Wu, Shaoxing, Hollis, Bruce, DeLuca, Hector F., Adams, John S., Hewison, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582909/
https://ncbi.nlm.nih.gov/pubmed/18535110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0060
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