The Antihypertensive Chromogranin A Peptide Catestatin Acts as a Novel Endocrine/Paracrine Modulator of Cardiac Inotropism and Lusitropism

Circulating levels of catestatin (Cts; human chromogranin A(352–372)) decrease in the plasma of patients with essential hypertension. Genetic ablation of the chromogranin A (Chga) gene in mice increases blood pressure and pretreatment of Chga-null mice with Cts prevents blood pressure elevation, ind...

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Hlavní autoři: Angelone, Tommaso, Quintieri, Anna Maria, Brar, Bhawanjit K., Limchaiyawat, Pauline T., Tota, Bruno, Mahata, Sushil K., Cerra, Maria Carmela
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582908/
https://ncbi.nlm.nih.gov/pubmed/18535098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0318
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