HP1-β is required for development of the cerebral neocortex and neuromuscular junctions

HP1 proteins are thought to be modulators of chromatin organization in all mammals, yet their exact physiological function remains unknown. In a first attempt to elucidate the function of these proteins in vivo, we disrupted the murine Cbx1 gene, which encodes the HP1-β isotype, and show that the Cb...

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Detalhes bibliográficos
Main Authors: Aucott, Rebecca, Bullwinkel, Jörn, Yu, Yang, Shi, Wei, Billur, Mustafa, Brown, Jeremy P., Menzel, Ursula, Kioussis, Dimitris, Wang, Guozheng, Reisert, Ingrid, Weimer, Jörg, Pandita, Raj K., Sharma, Girdhar G., Pandita, Tej K., Fundele, Reinald, Singh, Prim B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582898/
https://ncbi.nlm.nih.gov/pubmed/19015315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804041
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