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Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit

BubR1 kinase is essential for the mitotic checkpoint and also for kinetochores to establish microtubule attachments. In this study, we report that BubR1 is phosphorylated in mitosis on four residues that differ from sites recently reported to be phosphorylated by Plk1 (Elowe, S., S. Hummer, A. Uldsc...

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Main Authors: Huang, Haomin, Hittle, James, Zappacosta, Francesca, Annan, Roland S., Hershko, Avram, Yen, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582891/
https://ncbi.nlm.nih.gov/pubmed/19015317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805163
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