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p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression

p120 catenin regulates the activity of the Rho family guanosine triphosphatases (including RhoA and Rac1) in an adhesion-dependent manner. Through this action, p120 promotes a sessile cellular phenotype when associated with epithelial cadherin (E-cadherin) or a motile phenotype when associated with...

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Detalhes bibliográficos
Main Authors: Soto, Edwin, Yanagisawa, Masahiro, Marlow, Laura A., Copland, John A., Perez, Edith A., Anastasiadis, Panos Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582886/
https://ncbi.nlm.nih.gov/pubmed/19015320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805113
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