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T-cell co-stimulatory pathways in autoimmunity

T-cell activation and differentiation depend on the signal strength received by the T-cell receptor and on signals provided by co-stimulatory molecules. The most prominent co-stimulatory molecule is CD28, which controls the activation of naïve and memory T cells by antigen presented on professional...

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Autores principales: Goronzy, Jörg J, Weyand, Cornelia M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582810/
https://ncbi.nlm.nih.gov/pubmed/19007423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2414
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