Type IV Secretion-Dependent Activation of Host MAP Kinases Induces an Increased Proinflammatory Cytokine Response to Legionella pneumophila

The immune system must discriminate between pathogenic and nonpathogenic microbes in order to initiate an appropriate response. Toll-like receptors (TLRs) detect microbial components common to both pathogenic and nonpathogenic bacteria, whereas Nod-like receptors (NLRs) sense microbial components in...

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Detalhes bibliográficos
Main Authors: Shin, Sunny, Case, Christopher L., Archer, Kristina A., Nogueira, Catarina V., Kobayashi, Koichi S., Flavell, Richard A., Roy, Craig R., Zamboni, Dario S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582680/
https://ncbi.nlm.nih.gov/pubmed/19043549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000220
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