Low conservation and species-specific evolution of alternative splicing in humans and mice: comparative genomics analysis using well-annotated full-length cDNAs

Using full-length cDNA sequences, we compared alternative splicing (AS) in humans and mice. The alignment of the human and mouse genomes showed that 86% of 199 426 total exons in human AS variants were conserved in the mouse genome. Of the 20 392 total human AS variants, however, 59% consisted of al...

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Detalhes bibliográficos
Main Authors: Takeda, Jun-ichi, Suzuki, Yutaka, Sakate, Ryuichi, Sato, Yoshiharu, Seki, Masahide, Irie, Takuma, Takeuchi, Nono, Ueda, Takuya, Nakao, Mitsuteru, Sugano, Sumio, Gojobori, Takashi, Imanishi, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582632/
https://ncbi.nlm.nih.gov/pubmed/18838389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn677
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