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Enhanced gene trapping in mouse embryonic stem cells

Gene trapping is used to introduce insertional mutations into genes of mouse embryonic stem cells (ESCs). It is performed with gene trap vectors that simultaneously mutate and report the expression of the endogenous gene at the site of insertion and provide a DNA tag for rapid identification of the...

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Detalhes bibliográficos
Main Authors: Schnütgen, Frank, Hansen, Jens, De-Zolt, Silke, Horn, Carsten, Lutz, Marcus, Floss, Thomas, Wurst, Wolfgang, Noppinger, Patricia Ruiz, von Melchner, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582619/
https://ncbi.nlm.nih.gov/pubmed/18812397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn603
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