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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

A major challenge of the postgenomic era is the functional characterization of every single gene within the mammalian genome. In an effort to address this challenge, we assembled a collection of mutations in mouse embryonic stem (ES) cells, which is the largest publicly accessible collection of such...

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Detalhes bibliográficos
Main Authors: Hansen, Jens, Floss, Thomas, Van Sloun, Petra, Füchtbauer, Ernst-Martin, Vauti, Franz, Arnold, Hans-Hennig, Schnütgen, Frank, Wurst, Wolfgang, von Melchner, Harald, Ruiz, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187885/
https://ncbi.nlm.nih.gov/pubmed/12904583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633296100
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