Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathway

The Epstein–Barr virus (EBV)-encoded latent membrane protein-1 (LMP1), a functional homologue of the tumor necrosis factor receptor family, substantially contributes to EBV's oncogenic potential by activating nuclear factor-κB (NF-κB). miR-155 is an oncogenic miRNA critical for B-cell maturatio...

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Autors principals: Gatto, Graziana, Rossi, Annalisa, Rossi, Daniela, Kroening, Sven, Bonatti, Stefano, Mallardo, Massimo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582607/
https://ncbi.nlm.nih.gov/pubmed/18940871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn666
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