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The Mammalian Target of Rapamycin Complex 1 Regulates Leptin Biosynthesis in Adipocytes at the Level of Translation: The Role of the 5′-Untranslated Region in the Expression of Leptin Messenger Ribonucleic Acid

Leptin production by adipose cells in vivo is increased after feeding and decreased by food deprivation. However, molecular mechanisms that control leptin expression in response to food intake remain unknown. Here, we test the hypothesis that leptin expression in adipose cells is regulated by nutrie...

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Detalhes bibliográficos
Main Authors: Chakrabarti, Partha, Anno, Takatoshi, Manning, Brendan D., Luo, Zhijun, Kandror, Konstantin V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582535/
https://ncbi.nlm.nih.gov/pubmed/18653778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0148
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