Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase–generated superoxide

Environmental arsenic exposure, through drinking contaminated water, is a significant risk factor for developing vascular diseases and is associated with liver portal hypertension, vascular shunting, and portal fibrosis through unknown mechanisms. We found that the addition of low doses of arsenite...

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Main Authors: Straub, Adam C., Clark, Katherine A., Ross, Mark A., Chandra, Ashwin G., Li, Song, Gao, Xiang, Pagano, Patrick J., Stolz, Donna B., Barchowsky, Aaron
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582440/
https://ncbi.nlm.nih.gov/pubmed/19033667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35092
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