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Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase–generated superoxide

Environmental arsenic exposure, through drinking contaminated water, is a significant risk factor for developing vascular diseases and is associated with liver portal hypertension, vascular shunting, and portal fibrosis through unknown mechanisms. We found that the addition of low doses of arsenite...

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Detalhes bibliográficos
Main Authors: Straub, Adam C., Clark, Katherine A., Ross, Mark A., Chandra, Ashwin G., Li, Song, Gao, Xiang, Pagano, Patrick J., Stolz, Donna B., Barchowsky, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582440/
https://ncbi.nlm.nih.gov/pubmed/19033667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35092
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