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Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis

FGF signaling is associated with breast cancer and is required for mammary placode formation in the mouse. In this study, we employed a genetic mosaic analysis based on Cre-mediated recombination to investigate FGF receptor 2 (Fgfr2) function in the postnatal mammary gland. Mosaic inactivation of Fg...

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Détails bibliographiques
Auteurs principaux: Lu, Pengfei, Ewald, Andrew J., Martin, Gail R., Werb, Zena
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582391/
https://ncbi.nlm.nih.gov/pubmed/18585375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.06.005
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