Antigen-mediated T cell expansion regulated by parallel pathways of death

T cells enigmatically require caspase-8, an inducer of apoptosis, for antigen-driven expansion and effective antiviral responses, and yet the pathways responsible for this effect have been elusive. A defect in caspase-8 expression does not affect progression through the cell cycle but causes an abno...

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Detaylı Bibliyografya
Asıl Yazarlar: Ch'en, Irene L., Beisner, Daniel R., Degterev, Alexei, Lynch, Candace, Yuan, Junying, Hoffmann, Alexander, Hedrick, Stephen M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582294/
https://ncbi.nlm.nih.gov/pubmed/18981423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808043105
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