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Antigen-mediated T cell expansion regulated by parallel pathways of death
T cells enigmatically require caspase-8, an inducer of apoptosis, for antigen-driven expansion and effective antiviral responses, and yet the pathways responsible for this effect have been elusive. A defect in caspase-8 expression does not affect progression through the cell cycle but causes an abno...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582294/ https://ncbi.nlm.nih.gov/pubmed/18981423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808043105 |
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