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High stimulus unmasks positive feedback in an autoregulated bacterial signaling circuit
We examined the effect of positive autoregulation on the steady-state behavior of the PhoQ/PhoP two-component signaling system in Escherichia coli. We found that autoregulation has no effect on the steady-state output for a large range of input stimulus, which was modulated by varying the concentrat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582279/ https://ncbi.nlm.nih.gov/pubmed/18987315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807278105 |
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