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Adaptation to cell culture induces functional differences in measles virus proteins

BACKGROUND: Live, attenuated measles virus (MeV) vaccine strains were generated by adaptation to cell culture. The genetic basis for the attenuation of the vaccine strains is unknown. We previously reported that adaptation of a pathogenic, wild-type MeV to Vero cells or primary chicken embryo fibrob...

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Detalhes bibliográficos
Main Authors: Bankamp, Bettina, Fontana, Judith M, Bellini, William J, Rota, Paul A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582235/
https://ncbi.nlm.nih.gov/pubmed/18954437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-129
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