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Adaptation to cell culture induces functional differences in measles virus proteins

BACKGROUND: Live, attenuated measles virus (MeV) vaccine strains were generated by adaptation to cell culture. The genetic basis for the attenuation of the vaccine strains is unknown. We previously reported that adaptation of a pathogenic, wild-type MeV to Vero cells or primary chicken embryo fibrob...

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Hlavní autoři: Bankamp, Bettina, Fontana, Judith M, Bellini, William J, Rota, Paul A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582235/
https://ncbi.nlm.nih.gov/pubmed/18954437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-129
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