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Xenopus Kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline

The midline tissues are important inductive centers of early vertebrate embryos. By signal peptide selection screening, we isolated a secreted factor, Kielin, which contains multiple cys-rich repeats similar to those in chordin (Chd). Expression of Kielin starts at midgastrula stages in the notochor...

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Bibliographic Details
Main Authors: Matsui, Masaru, Mizuseki, Kenji, Nakatani, Jin, Nakanishi, Shigetada, Sasai, Yoshiki
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25821/
https://ncbi.nlm.nih.gov/pubmed/10779551
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