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Cell-autonomous requirement for β1 integrin in endothelial cell adhesion, migration, and survival during angiogenesis in mice

β1 integrin is established as a regulator of angiogenesis based upon the phenotypes of complete knockout of β1 heterodimer partners or ligands and antibody inhibition studies in mice. Its direct function in endothelial cells (ECs) in vivo has not been determined because β1(−/−) embryos die before va...

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Bibliographische Detailangaben
Hauptverfasser: Carlson, Timothy R., Hu, Huiqing, Braren, Rickmer, Kim, Yung Hae, Wang, Rong A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582018/
https://ncbi.nlm.nih.gov/pubmed/18480158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.016378
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