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Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation

Morphogenesis of a vascular network requires dynamic vessel growth and regression. To investigate the cellular mechanism underlying this process, we deleted focal adhesion kinase (FAK), a key signaling mediator, in endothelial cells (ECs) using Tie2-Cre mice. Targeted FAK depletion occurred efficien...

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Detaylı Bibliyografya
Asıl Yazarlar: Braren, Rickmer, Hu, Huiqing, Kim, Yung Hae, Beggs, Hilary E., Reichardt, Louis F., Wang, Rong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063542/
https://ncbi.nlm.nih.gov/pubmed/16391003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200506184
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