Mononuclear myeloid-derived “suppressor” cells express RAE-1 and activate natural killer cells

Myeloid-derived suppressor cells (MDSCs) accumulate in cancer patients and tumor-bearing mice and potently suppress T-cell activation. In this study, we investigated whether MDSCs regu-late natural killer (NK)–cell function. We discovered that mononuclear Gr-1(+)CD11b(+)F4/80(+) MDSCs isolated from...

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Autores principales: Nausch, Norman, Galani, Ioanna E., Schlecker, Eva, Cerwenka, Adelheid
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2008
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582006/
https://ncbi.nlm.nih.gov/pubmed/18753637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-143776
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