Natural killer T-cell autoreactivity leads to a specialized activation state

Natural killer T (NKT) cells are innate-like T cells that recognize specific microbial antigens and also display autoreactivity to self-antigens. The nature of NKT-cell autoreactive activation remains poorly understood. We show here that the mitogen-activated protein kinase (MAPK) pathway is operati...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xiaohua, Chen, Xiuxu, Rodenkirch, Lance, Simonson, William, Wernimont, Sarah, Ndonye, Rachel M., Veerapen, Natacha, Gibson, Darren, Howell, Amy R., Besra, Gurdyal S., Painter, Gavin F., Huttenlocher, Anna, Gumperz, Jenny E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2008
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581981/
https://ncbi.nlm.nih.gov/pubmed/18779390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157529
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