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Human invariant natural killer T cells acquire transient innate responsiveness via histone H4 acetylation induced by weak TCR stimulation

Invariant NKT cells (iNKT cells) are innate T lymphocytes that are thought to play an important role in producing an early burst of IFN-γ that promotes successful tumor immunosurveillance and antimicrobial immunity. The cellular activation processes underlying innate IFN-γ production remain poorly u...

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Hlavní autoři: Wang, Xiaohua, Bishop, Kathleen A., Hegde, Subramanya, Rodenkirch, Lance A., Pike, J. Wesley, Gumperz, Jenny E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348100/
https://ncbi.nlm.nih.gov/pubmed/22508835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111024
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