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Transmission Dynamics of Heritable Silencing Induced by Double-Stranded RNA in Caenorhabditis elegans

Heritable silencing effects are gene suppression phenomena that can persist for generations after induction. In the majority of RNAi experiments conducted in Caenorhabditis elegans, the silencing response results in a hypomorphic phenotype where the effects recede after the F(1) generation. F(2) and...

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Bibliografske podrobnosti
Main Authors: Alcazar, Rosa M., Lin, Rueyling, Fire, Andrew Z.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581934/
https://ncbi.nlm.nih.gov/pubmed/18757930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089433
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