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Reciprocal Regulation of Extracellular Signal Regulated Kinase 1/2 and Mitogen Activated Protein Kinase Phosphatase-3

Mitogen activated protein kinase phosphatase-3 (MKP-3) is a putative tumor suppressor. When transiently overexpressed, MKP-3 dephosphorylates and inactivates extracellular signal regulated kinase (ERK) 1/2. Little is known about the roles of endogenous MKP-3, however. We previously showed that MKP-3...

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Detalhes bibliográficos
Main Authors: Zeliadt, Nicholette A., Mauro, Laura J., Wattenberg, Elizabeth V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581931/
https://ncbi.nlm.nih.gov/pubmed/18771677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.08.007
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