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Reciprocal Regulation of Extracellular Signal Regulated Kinase 1/2 and Mitogen Activated Protein Kinase Phosphatase-3
Mitogen activated protein kinase phosphatase-3 (MKP-3) is a putative tumor suppressor. When transiently overexpressed, MKP-3 dephosphorylates and inactivates extracellular signal regulated kinase (ERK) 1/2. Little is known about the roles of endogenous MKP-3, however. We previously showed that MKP-3...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581931/ https://ncbi.nlm.nih.gov/pubmed/18771677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.08.007 |
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