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In Vitro Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors in Sandwich-Cultured Rat Hepatocytes: Comparison to In Vivo Biliary Clearance

Previous reports have indicated that in vitro biliary clearance (Cl(biliary)) determined in sandwich-cultured hepatocytes correlates well with in vivo Cl(biliary) for limited sets of compounds. This study was designed to estimate the in vitro Cl(biliary) in sandwich-cultured rat hepatocytes (SCRH) o...

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Hlavní autoři: Abe, Koji, Bridges, Arlene S., Yue, Wei, Brouwer, Kim L. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581923/
https://ncbi.nlm.nih.gov/pubmed/18574002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.138073
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