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A Critical Role of a Cellular Membrane Traffic Protein in Poliovirus RNA Replication

Replication of many RNA viruses is accompanied by extensive remodeling of intracellular membranes. In poliovirus-infected cells, ER and Golgi stacks disappear, while new clusters of vesicle-like structures form sites for viral RNA synthesis. Virus replication is inhibited by brefeldin A (BFA), impli...

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Detalhes bibliográficos
Main Authors: Belov, George A., Feng, Qian, Nikovics, Krisztina, Jackson, Catherine L., Ehrenfeld, Ellie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581890/
https://ncbi.nlm.nih.gov/pubmed/19023417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000216
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