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Bacterial expression and purification of Interleukin-2 Tyrosine kinase: Single step separation of the chaperonin impurity

Biochemical and biophysical characterization of kinases requires large quantities of purified protein. Here we report the bacterial expression and purification of active Itk kinase domain (a Tec family kinase) using ArcticExpress cells that co-express the chaperonin system Cpn60/10 from Oleispira an...

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Bibliografske podrobnosti
Main Authors: Joseph, Raji E., Andreotti, Amy H.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581883/
https://ncbi.nlm.nih.gov/pubmed/18495488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2008.04.001
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