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Activation of an IL-6:STAT3-dependent Transcriptome in Pediatric-onset Inflammatory Bowel Disease

BACKGROUND: While activation of the IL-6-dependent transcription factor signal transducer and activator of transcription 3 (STAT3) has been implicated in the pathogenesis of inflammatory bowel disease (IBD), a direct effect on mucosal gene expression and inflammation has not been shown. We hypothesi...

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Detalhes bibliográficos
Main Authors: Carey, Rebecca, Jurickova, Ingrid, Ballard, Edgar, Bonkowski, Erin, Han, Xiaonan, Xu, Huan, Denson, Lee A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581837/
https://ncbi.nlm.nih.gov/pubmed/18069684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20342
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