Eicosapentaenoic-acid-derived Isoprostanes: Synthesis and Discovery of Two Major Isoprostanes

The stereospecific synthesis of two all-syn-EPA-derived isoprostanes (iPs), 5-epi-8,12-iso-iPF(3α)-VI 17 and 8,12-iso-iPF(3α)-VI 18, has been accomplished. These two synthetic probes have been used to discover and identify their presence in human urine. The eventual quantitative measurement of these...

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Hlavní autoři: Chang, Chih-Tsung, Patel, Pranav, Kang, Namin, Lawson, John A., Song, Wen-Liang, Powell, William S., FitzGerald, Garret A., Rokach, Joshua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581611/
https://ncbi.nlm.nih.gov/pubmed/18804370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.09.008
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