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Differential Roles of the COOH Termini of AAA Subunits of PA700 (19 S Regulator) in Asymmetric Assembly and Activation of the 26 S Proteasome

The 26 S proteasome is an energy-dependent protease that degrades proteins modified with polyubiquitin chains. It is assembled from two multi-protein subcomplexes: a protease (20 S proteasome) and an ATPase regulatory complex (PA700 or 19 S regulatory particle) that contains six different AAA family...

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Bibliografske podrobnosti
Main Authors: Gillette, Thomas G., Kumar, Brajesh, Thompson, David, Slaughter, Clive A., DeMartino, George N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581596/
https://ncbi.nlm.nih.gov/pubmed/18796432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805935200
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