Chromatin Modification Requirements for 15-Lipoxygenase-1 Transcriptional Reactivation in Colon Cancer Cells

15-Lipoxygenase-1 (15-LOX-1) contributes significantly to inflammation regulation and terminal cell differentiation. 15-LOX-1 is transcriptionally silenced in cancer cells, and its transcriptional reactivation (e.g. via histone deacetylase inhibitors (HDACIs)) is essential for restoring terminal cel...

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Bibliographic Details
Main Authors: Zuo, Xiangsheng, Morris, Jeffrey S., Shureiqi, Imad
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581547/
https://ncbi.nlm.nih.gov/pubmed/18799463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803729200
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