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Modulation of PGC-1 Coactivator Pathways in Brown Fat Differentiation through LRP130
The PGC-1 coactivators are important regulators of oxidative metabolism. We previously demonstrated that LRP130 is a binding partner of PGC-1α, required for hepatic gluconeogenesis. LRP130 is the gene mutated in Leigh syndrome French Canadian variant, a rare neurodegenerative disease. The importance...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581541/ https://ncbi.nlm.nih.gov/pubmed/18728005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805431200 |
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