Modulation of PGC-1 Coactivator Pathways in Brown Fat Differentiation through LRP130

The PGC-1 coactivators are important regulators of oxidative metabolism. We previously demonstrated that LRP130 is a binding partner of PGC-1α, required for hepatic gluconeogenesis. LRP130 is the gene mutated in Leigh syndrome French Canadian variant, a rare neurodegenerative disease. The importance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cooper, Marcus P., Uldry, Marc, Kajimura, Shingo, Arany, Zoltan, Spiegelman, Bruce M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Metabolism and Bioenergetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581541/
https://ncbi.nlm.nih.gov/pubmed/18728005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805431200
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