Ca(2+) Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites

Cyclic ADP-ribose is an important Ca(2+)-mobilizing cytosolic messenger synthesized from β-NAD(+) by ADP-ribosyl cyclases (ARCs). However, the focus upon ectocellular mammalian ARCs (CD38 and CD157) has led to confusion as to how extracellular enzymes generate intracellular messengers in response to...

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Bibliographische Detailangaben
Hauptverfasser: Davis, Lianne C., Morgan, Anthony J., Ruas, Margarida, Wong, Julian L., Graeff, Richard M., Poustka, Albert J., Lee, Hon Cheung, Wessel, Gary M., Parrington, John, Galione, Antony
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2008
Schlagworte:
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581485/
https://ncbi.nlm.nih.gov/pubmed/18951023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.09.024
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