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A simple, quick and high-yield preparation of the human thromboxane A2 receptor in full size for structural studies

Human thromboxane A2 receptor (TP), a G protein-coupled receptor (GPCR), is one of the most promising targets for developing the next generation of anti-thrombosis and hypertension drugs. However, obtaining a sufficient amount of the full sized and active membrane protein has been the major obstacle...

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Autori principali: Ruan, Ke-He, Cervantes, Vanessa, Wu, Jiaxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581465/
https://ncbi.nlm.nih.gov/pubmed/18529068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702501g
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