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Characterization of the Prostaglandin H(2) Mimic: Binding to the Purified Human Thromboxane A(2) Receptor in Solution

For decades, the binding of prostaglandin H(2) (PGH(2)) to multiple target proteins of unrelated protein structures which mediate diverse biological functions has remained a real mystery in the field of eicosanoid biology. Here, we report that the structure of a PGH(2) mimic, U46619, bound to the pu...

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Sonraí Bibleagrafaíochta
Main Authors: Ruan, Ke-He, Wijaya, Cori, Cervantes, Vanessa, Wu, Jiaxin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572108/
https://ncbi.nlm.nih.gov/pubmed/18590695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.05.022
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