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Characterization of the Prostaglandin H(2) Mimic: Binding to the Purified Human Thromboxane A(2) Receptor in Solution

For decades, the binding of prostaglandin H(2) (PGH(2)) to multiple target proteins of unrelated protein structures which mediate diverse biological functions has remained a real mystery in the field of eicosanoid biology. Here, we report that the structure of a PGH(2) mimic, U46619, bound to the pu...

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Detalhes bibliográficos
Main Authors: Ruan, Ke-He, Wijaya, Cori, Cervantes, Vanessa, Wu, Jiaxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572108/
https://ncbi.nlm.nih.gov/pubmed/18590695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.05.022
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