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Characterization of the Prostaglandin H(2) Mimic: Binding to the Purified Human Thromboxane A(2) Receptor in Solution
For decades, the binding of prostaglandin H(2) (PGH(2)) to multiple target proteins of unrelated protein structures which mediate diverse biological functions has remained a real mystery in the field of eicosanoid biology. Here, we report that the structure of a PGH(2) mimic, U46619, bound to the pu...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572108/ https://ncbi.nlm.nih.gov/pubmed/18590695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.05.022 |
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