Characterization of the Prostaglandin H(2) Mimic: Binding to the Purified Human Thromboxane A(2) Receptor in Solution

For decades, the binding of prostaglandin H(2) (PGH(2)) to multiple target proteins of unrelated protein structures which mediate diverse biological functions has remained a real mystery in the field of eicosanoid biology. Here, we report that the structure of a PGH(2) mimic, U46619, bound to the pu...

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Bibliographic Details
Main Authors:	Ruan, Ke-He, Wijaya, Cori, Cervantes, Vanessa, Wu, Jiaxin
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2572108/ https://ncbi.nlm.nih.gov/pubmed/18590695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.05.022
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Characterization of the Prostaglandin H(2) Mimic: Binding to the Purified Human Thromboxane A(2) Receptor in Solution

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